| Registro completo |
| Provedor de dados: |
ArchiMer
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| País: |
France
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| Título: |
Infectivity and RNA Persistence of a Norovirus Surrogate, the Tulane Virus, in Oysters
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| Autores: |
Polo, David
Schaeffer, Julien
Teunis, Peter
Buchet, Vincent
Le Guyader, Soizick
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| Data: |
2018-04
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| Ano: |
2018
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| Palavras-chave: |
Infectious virus
Genome detection
Oysters
Persistence
Shellfish outbreaks
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| Resumo: |
Oysters, being filter feeders, can accumulate some human pathogens such as norovirus, a highly infectious calicivirus, most common cause of acute gastroenteritis worldwide. Accumulated virus decays over a period of days to weeks, possibly rendering contaminated oysters safe again. Sensitive molecular methods have been set up for shellfish analysis but without answering the question of infectious virus detection. Using the Tulane virus (TV), a norovirus surrogate that recognizes the same ligand as human norovirus in oyster tissues, the genome and infectious virus decay rates were estimated using inverse linear regression in a Bayesian framework for genome copies. Infectivity decreased faster than genome copies but infectious viruses were detected for several days. Quantifying the decrease in viral infectivity and genome detection in oysters over such a long period may help local authorities to manage production areas implicated in shellfish-borne outbreaks, and thus protect consumers.
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| Tipo: |
Text
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| Idioma: |
Inglês
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| Identificador: |
https://archimer.ifremer.fr/doc/00436/54736/56182.pdf
https://archimer.ifremer.fr/doc/00436/54736/56184.pdf
DOI:10.3389/fmicb.2018.00716
https://archimer.ifremer.fr/doc/00436/54736/
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| Editor: |
Frontiers Media Sa
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| Relação: |
info:eu-repo/grantAgreement/EC/FP7/643476/EU//COMPARE
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| Formato: |
application/pdf
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| Fonte: |
Frontiers In Microbiology (1664-302X) (Frontiers Media Sa), 2018-04 , Vol. 9 , N. 716 , P. 8p.
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| Direitos: |
2018 Polo, Schaeffer, Teunis, Buchet and Le Guyader. This is an openaccess article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction...
info:eu-repo/semantics/openAccess
restricted use
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